MSTest vs Intern comparison of testing frameworks
What are the differences between MSTest and Intern?

MSTest

https://github.com/microsoft/testfx-docs

Intern

https://github.com/theintern/intern
Programming language

.NET

JavaScript

Category

Unit Testing

Unit Testing, Functional Testing

General info

MSTest is a Unit testing framework for the .net framework

MSTest is fully integrated with Visual Studios and works natively without the need for any plugins. MSTest is better suited for only using Microsoft technologies rather than mixed technology environments.

Intern is minimal test system for JavaScript designed to write and run consistent.

Intern is a complete test system for JavaScript designed to help you write and run consistent, high-quality test cases for your JavaScript libraries and applications. Using Intern we can write tests in JavaScript and TypeScript using any style like TDD, and BDD. Intern can run unit tests in most browsers that support ECMAScript
xUnit
Set of frameworks originating from SUnit (Smalltalk's testing framework). They share similar structure and functionality.

Yes

MsTest is an xUnit type framework

No

Client-side
Allows testing code execution on the client, such as a web browser

Yes

MsTest can test various front-end components

Yes

Intern is a complete test system for JavaScript It Runs in the browser and can test any front-end component and functionality
Server-side
Allows testing the bahovior of a server-side code

Yes

With MSTest you can test various back-end components individually

Yes

Since it is a complete testing system that can test any type of JavaScript code, it can test server-side behaviour and components as well
Fixtures
Allows defining a fixed, specific states of data (fixtures) that are test-local. This ensures specific environment for a single test

Yes

MSTest contains fixture methods TestInitialize to setup your environment and TestCleanup to destroy the test environment

N/A

Group fixtures
Allows defining a fixed, specific states of data for a group of tests (group-fixtures). This ensures specific environment for a given group of tests.

Yes

Group fixtures are available

N/A

Generators
Supports data generators for tests. Data generators generate input data for test. The test is then run for each input data produced in this way.

N/A

Licence
Licence type governing the use and redistribution of the software

Creative Commons Attribution 3.0 International Public License

FreeBSD License

Mocks
Mocks are objects that simulate the behavior of real objects. Using mocks allows testing some part of the code in isolation (with other parts mocked when needed)

Yes

You can create mock objects using the third party library moq

Intern uses the Dojo Toolkit’s AMD loader. To mock, you should be able to just use the standard AMD 'map' feature, else you can use third party libraries like sinon.js
Grouping
Allows organizing tests in groups

Yes

Grouping of tests into suites is possible with MSTest

Yes

You can group tests into Suites which may be specified as file paths or using glob expressions, there is typically one top-level suite per module.
Other
Other useful information about the testing framework