Unit.js vs MSTest comparison of testing frameworks
What are the differences between Unit.js and MSTest?

Unit.js

https://unitjs.com/

MSTest

https://github.com/microsoft/testfx-docs
Programming language

JavaScript

.NET

Category

Unit Testing, End-to-End Testing

Unit Testing

General info

An assertion library for JavaScript (similar to chai.js)

It works with any test runner and unit testing framework like Mocha, Jasmine, Karma, protractor (E2E test framework for Angular apps) and QUnit.

MSTest is a Unit testing framework for the .net framework

MSTest is fully integrated with Visual Studios and works natively without the need for any plugins. MSTest is better suited for only using Microsoft technologies rather than mixed technology environments.
xUnit
Set of frameworks originating from SUnit (Smalltalk's testing framework). They share similar structure and functionality.

Yes

MsTest is an xUnit type framework
Client-side
Allows testing code execution on the client, such as a web browser

Yes

Unit.js runs in the browser to test front-end components

Yes

MsTest can test various front-end components
Server-side
Allows testing the bahovior of a server-side code

Yes

Unit.js runs in nodejs to test server-side behaviour

Yes

With MSTest you can test various back-end components individually
Fixtures
Allows defining a fixed, specific states of data (fixtures) that are test-local. This ensures specific environment for a single test

Yes

Unit.js provides Test fixtures for running testsThis is one of its features

Yes

MSTest contains fixture methods TestInitialize to setup your environment and TestCleanup to destroy the test environment
Group fixtures
Allows defining a fixed, specific states of data for a group of tests (group-fixtures). This ensures specific environment for a given group of tests.

Yes

With Unit.js you can group your fixtures

Yes

Group fixtures are available
Generators
Supports data generators for tests. Data generators generate input data for test. The test is then run for each input data produced in this way.

N/A

Licence
Licence type governing the use and redistribution of the software

GNU

Creative Commons Attribution 3.0 International Public License

Mocks
Mocks are objects that simulate the behavior of real objects. Using mocks allows testing some part of the code in isolation (with other parts mocked when needed)

N/A

Yes

You can create mock objects using the third party library moq
Grouping
Allows organizing tests in groups

N/A

Yes

Grouping of tests into suites is possible with MSTest
Other
Other useful information about the testing framework